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| Benzoyl Peroxide |
- First used for treatment of acne in 1979 as a potent topical bactericidal agent.
- Reduces the population of Propionibacterium acnes (P. acnes) by generating ROS (Reactive Oxygen Species) within the sebaceous follicle.
- Effective against inflammatory and non-inflammatory lesions.
- Treats acne bacteria as early as 5 days after initiation of treatment.
- Offered in a wide variety of preparations: cleansers, lotions, creams, gels and pads.
- Reduction in P. acnes is greater with leave-on products but wash off products are very effective.
- The sale of OTC BPO far exceeds that of other OTC acne treatments.
- When compared with other topical antimicrobials, 5% BPO was found to be at least as effective for acne as erythromycin and clindamycin formulations.
- BPO has the ability to prevent or eliminate the development of P. acnes resistance.
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